Henri-Baptiste Marjault was born in 1989 in Vernon, France. He graduated from the University of Versailles Saint-Quentin-en-Yveline (France), with a bachelor’s degree in Biology. He continued his studies at the University of Saclay (France) with a Master in Biology (Gene Cell Development). In his Master thesis, he worked on the analysis of the effects of low radiation doses on spermatogenesis in adult mices.
His current research interests lie in the interaction between the iron-sulfur NEET proteins and neurodegeneration, in particular investigation of the binding of ligand known to interfere with fibril formation in α-synuclein. The human α-synuclein protein is associated with the pathogenesis of PD and other neurodegenerative disorders. Rational ligand design towards α-synuclein is hampered by its complexity. HPC-based computational protocols for the investigation of intrinsically disordered proteins such as α-synuclein will be developed further to model the physiological form of human α-synuclein.
Henri-Baptiste has been selected for the position of ESR6 with joint degree awarding institutions Hebrew University of Jerusalem (Israel), RWTH Aachen University (Germany) and The Cyprus Institute (Cyprus). The project entitled «Investigation of α-synuclein/ligand interactions" is supervised by Prof. Rachel Nechushtai, Prof. Paolo Carloni and Assist. Prof. Giannis Koutsou.